Awọn ọna aabo amino ti o wọpọ
1. Cbz
Benzyloxycarbonyl (Cbz) Amino ni idaabobo
Idabobo ti N-benzyloxycarbonyl (Cbz)
Awọn reagents ti o wọpọ - CbzCl
2. Aloc
Allyloxycarbonyl (Alloc) ti o ni aabo ẹgbẹ amino
3. Trifluoroacetyl
Ẹgbẹ amino ti o ni idaabobo Trifluoroacetyl
4. Benzyls
p-methoxybenzyl (PMB) ẹgbẹ amino ti o ni aabo
2,4-dimethoxybenzyl ẹgbẹ amino ti o ni aabo
Amino ni idaabobo Benzyl
Idabobo ti ẹgbẹ amino ti o ni idaabobo benzyl
N-Bn debenzylation nipasẹ ọna chloroformate
5. Pht (phthaloyl)
Phthaloyl (Pht) awọn ẹgbẹ amino ti o ni aabo
Idabobo ti ẹgbẹ amino ti o ni aabo phthaloyl
6. Benzenesulfonyl
Nitrobenzenesulfonyl ni idaabobo ẹgbẹ amino
p-toluenesulfonyl (Tos) amino Idaabobo
7. Trt
Tril ni idaabobo amino
Idaabobo ti ẹgbẹ amino ti o ni idaabobo trityl
8. Boc
Tert-butoxycarbonyl ti o ni aabo ẹgbẹ amino
Idabobo ti N-tert-butoxycarbonyl
Oxalyl kiloraidi De-Boc
9. Fmoc
Wat methoxycarbonyl amino Ẹgbẹ aabo
Awọn reagents ti o wọpọ - Fmoc-Cl
10. SEM
SEM ni idaabobo amino
11. Awọn miiran
Acetamide ni aabo ẹgbẹ amino
Idahun iṣelọpọ Clauson-Kaas pyrrole (idahun yii le ṣee lo bi ọna lati daabobo awọn ẹgbẹ amino, le rọpo aabo Boc meji, ati pe o jẹ iduroṣinṣin diẹ sii)
Awọn reagents ti o wọpọ - benzyl (chloromethyl) ether
Awọn reagents ti o wọpọ - (chloromethyl) methyl ether [MOMCl]
Carbamate Idaabobo
Akoko ifiweranṣẹ: Oṣu Kẹsan-07-2023