asia_oju-iwe

15260-10-3 Tert-butoxycarbonyl-L-threonine(benzyl)-OH

15260-10-3 Tert-butoxycarbonyl-L-threonine(benzyl) -OH Aworan Ifihan
  • 15260-10-3 Tert-butoxycarbonyl-L-threonine(benzyl)-OH
  • 15260-10-3 Tert-butoxycarbonyl-L-threonine(benzyl)-OH
  • 15260-10-3 Tert-butoxycarbonyl-L-threonine(benzyl)-OH

15260-10-3 Tert-butoxycarbonyl-L-threonine(benzyl)-OH

Apejuwe kukuru:

Ifarahan Funfun si Paa-White kirisita tabi kirisita lulú.
MF C16H23NO5
MW 309.36
Mimo 98+


Alaye ọja

Ipo gbigbe&ọna gbigbe ti a ṣeduro:
nipasẹ afẹfẹ, nipasẹ okun tabi nipasẹ kiakia

Ipo ipamọ:
Tọju ni aaye dudu, Ti di ni gbigbẹ, Iwọn otutu yara

Ibere ​​ti o kere ju Qty:
Idunadura

Ijẹrisi:
COA, HPLC, GC, HNMR, Assay, Omi Akoonu(KF), TLC wa

D-Lys(tfa) -NCA (2)

Awọn itumọ ọrọ sisọ

Boc-O-Benzyl-L-threonine;
BOC-THR-OH;
BOC-THR (BZL) -OH;
Butoxacarbonylbenzylthreonine;
NT-boc-O-benzyl-L-threonine * crystalline;
O-benzyl-N-tert-butoxycarbonyl-L-threonine;
N-ALPHA-T-BUTYLOXYCARBONYL-O-BENZYL-L-THREONINE;
NALPHA-tert-Butoxycarbonyl-O-benzyl-L-threonine

akojọpọ Iṣakojọpọ

Wọn ti wa ni maa lo lati lowo etu.Ati pe wọn le ṣe idiwọ oorun ati omi lati di buburu.

Iṣakojọpọ inu 2
Iṣakojọpọ inu 1
Iṣakojọpọ inu 3

lode packing

Paali lile le daabobo awọn ọja rẹ lati jamba ati jijẹ tutu.

Iṣakojọpọ lode 3
Iṣakojọpọ ita 2
Iṣakojọpọ ita 1

Awọn ohun elo

Funfun okuta lulú;Insoluble ninu omi ati epo ether, tiotuka ni ethyl acetate ati kẹmika;mp jẹ 115-116 ℃;Yiyi kan pato [α]20D+15.8°(0.5-2.0 mg/ml, kẹmikali).
Ti a lo fun iṣelọpọ polypeptide, bi monomer aabo amino acid.
O-benzyl-l-threonine ti daduro ni ojutu dioxane ati acylated pẹlu tert-butylcarbonyl azide lati gba ọja robi, eyiti a fa jade nipasẹ ethyl acetate ni pH ti 9-10 ati lẹhinna tun ṣe atunṣe.
Apa ti nṣiṣe lọwọ ti thymic oietin Ⅱ ti awọn aṣiri thymus.Thymoietin II jẹ apopọ polypeptide kan ti o ya sọtọ lati homonu thymus.O ni awọn amino acids 49, ati peptide pq ajẹkù ti o ni awọn amino acids 5 ni gbogbo awọn iṣẹ iṣe ti ẹkọ iṣe-iṣe kanna bi thymoietin II.Nitorina, ajẹkù pentapeptide yii ni a npe ni thymus pentapeptide.Funfun di-si dahùn o alaimuṣinṣin ibi-tabi lulú.
Ọkan ninu awọn ipa ti thymus pentapeptide ni lati fa iyatọ sẹẹli T.O le ni yiyan fa iyipada ti awọn sẹẹli Thy-1-prothorax sinu awọn sẹẹli Thy-1+ T.Iyatọ sẹẹli T jẹ ilaja nipasẹ awọn ipele cAMP intracellular ti o pọ si.Iṣẹ ipilẹ miiran ti awọn pentapeptides thymus ni lati sopọ si awọn olugba kan pato ti awọn sẹẹli ẹjẹ agbeegbe ti ogbo, mu ipele cAMP intracellular pọsi, ati nitorinaa fa lẹsẹsẹ awọn aati intracellular, eyiti o tun jẹ ipilẹ ti iṣẹ imunomodulatory rẹ.Ni ipo ara deede, thymus pentapeptide ṣe afihan ipa imunilọrun ajẹsara, eyiti o le ṣe alekun oṣuwọn idasile E rosette ni pataki ati iwọn iyipada ti awọn lymphocytes splenic, mu awọn ipele oriṣiriṣi ti idahun ajẹsara akọkọ tabi atẹle pọ si, ati mu nọmba IgM iru ati IgG pọ si tabi IgA iru antibody lara awọn sẹẹli.Thymus pentapeptide tun le mu iṣẹ phagocytosis ti awọn macrophages pọ si, mu enzymu ati iṣẹ phagocytosis ti awọn neutrophils polymorphonuclear, mu akoonu antibody kaakiri, ati mu iṣẹ ajẹsara ti awọn sẹẹli ẹjẹ pupa pọ si.Thymus pentapeptide le mu CD4 ati awọn sẹẹli rere CD8 ṣiṣẹ, ki awọn sẹẹli Tc kan pato le ṣetọju igbesi aye gigun, ṣugbọn tun le mu awọn sẹẹli Th ṣiṣẹ ati mu iṣẹ awọn sẹẹli Ts ṣiṣẹ.Awọn ipa apakokoro ati itọju ti thymus pentapeptide ni ibatan si imudara rẹ ti iṣẹ ṣiṣe sẹẹli TC.Iwọn ti o yẹ ti pentapeptide thymus le ṣe alekun iṣelọpọ ti interferon ni pataki ni ajesara egboogi-kokoro.Inducing ati igbega T cell iyatọ ati maturation;CD4/CD8 maa n jẹ deede nipa ṣiṣatunṣe ipin ti T lymphocyte subsets;Ṣe ilọsiwaju iṣẹ phagocytosis ti macrophages;Ṣe ilọsiwaju iṣẹ ajẹsara ẹjẹ ẹjẹ pupa;Mu iṣẹ ṣiṣe ti awọn sẹẹli apaniyan adayeba pọ si;Mu ipele ti iṣelọpọ interleukin-2 pọ si ati ikosile olugba;Ṣe ilọsiwaju iṣelọpọ γ interferon ninu awọn sẹẹli mononuclear ẹjẹ agbeegbe;Ṣe ilọsiwaju iṣẹ SOD ni omi ara.
O le ṣee lo ni awọn alaisan tumo buburu pẹlu ailagbara iṣẹ ajẹsara lẹhin radiotherapy ati kimoterapi.Itoju ti jedojedo B;Awọn iṣẹ abẹ nla ati awọn akoran ti o lagbara;Awọn arun autoimmune gẹgẹbi arthritis rheumatoid, lupus erythematosus;Iru II àtọgbẹ mellitus, menopause dídùn;Eniyan ti o ni iṣẹ ajẹsara alailagbara.

jẹmọ awọn ọja

Fmoc-L-Thr (tBu) -Phe-OH Boc-D-Thr-OH
HL-Thr-OH Boc-D-Thr (mi) -OH
DL-Thr Boc-D-Thr (Bzl) -OH
HL-allo-Thr-OH Cbz-Thr-OH
L-Thr(bzl) Cbz-Thr-Obzl
HL-Thr (tBu) -OH ZL-Thr-ome
L-Thr(mi) Cbz-D-Thr-OH
Thr-Otbu.hcl Cbz-L-Thr (tBu) -OH
L-Thr (bzl).HCl Cbz-L-Thr (bzl)-OH
L-Thr (mi).Hcl Cbz-L-Thr (tBu) -OH DCHA
L-Thr-Obzl.HCl Fmoc-L-Thr-OH
HL-Thr-OMe.HCl fmoc-L-Thr-OtBu
L-Thr-Oet.Hcl Fmoc-L-Thr-Obzl
L-Allo-Thr-Ome.Hcl Fmoc-L-Allo-Thr-OH
HL-Thr-OBzl·oxalate Fmoc-Thr (tBu) -OH
D-Thr (bzl).HCl Fmoc-L-Thr (bzl)-OH
D-Thr-Oet.Hcl Fmoc-D-Thr-OH
D-Thr-Obzl.HCl Fmoc-D-Thr (bzl)-OH
D-Thr-Ome.HCl Fmoc-D-Thr (tBu) -OH
DL-Thr-Ome.HCl Fmoc-L-Thr (tBu) -Ser-OH
Boc-L-Thr-OtBu Boc-n-me-l-thr (bzl).CHA
Boc-L-Thr-OH Fmoc-N-Me-L-Thr (bzl) -OH
Boc-L-allo-Thr-OH Fmoc-L-Thr (tBu) -Gly-OH
Boc-Thr-OMe (2S,3S)-2-Amino-3-methoxybutanoic acid/L-AlloThr(Mi)
Boc-Thr-Obzl (2S,3S)-2-Amino-3-methoxybutanoic acid/BOC-AlloThr(Mi)
Boc-L-Thr (tBu) -OH HL-Thr (Bzl) -OBzl.oxalate
Boc-L-Thr (Bzl) -OH Boc-D-Thr-Ome
Boc-L-Thr (mi) -OH

Iwaju

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3.A ni kikun ilana ti iṣẹ atẹle lakoko iṣelọpọ
4.High iye owo to munadoko
Awọn iwe-ẹri 5.Quality ti a pese fun ibeere alabara
6.Great lẹhin-tita iṣẹ, mimu sunmọ ibasepo pẹlu onibara
7.Full awọn oluşewadi lati ṣe iranlọwọ lati dinku awọn idiyele gbigbe
8.Free ayẹwo ti a nṣe lati ṣayẹwo didara ṣaaju si eyikeyi sisanwo
9.Payment igba idunadura
Awọn alabara 10.Assit ṣe pẹlu awọn ọran ni Ilu China

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